ImSimQA™ Base Module
This the underlying software to which optional modules can be added. This module includes a virtual phantom library, manipulation of DICOM-3 images and the creation of new DICOM images for testing clinical applications.
Virtual phantom library
The virtual phantom library contains a library of 25 3D anatomical and geometric virtual phantoms, all of which can be extensively edited and exported as DICOM-3 images, to create uniquely customisable phantoms which offer an infinite range of testing potential. All virtual phantoms can be transformed, deformed, re-orientated, structure density changed etc, to create DICOM-3 series in CT, simulated MR and PET which are then exported to the test application. DICOM headers can be edited. Parameters such as slice spacing and FOV can be modified in the exported DICOM-3 series.
Manipulation of DICOM-3 images
DICOM-3 images of any modality can be imported, edited and exported as new DICOM series. Supported modalities include CT, MR, PET, MVCT and cone beam CT. RT Structure Sets can be imported, and edited prior to export. A selection of noise patterns can be added to images.
DICOM images can be globally translated, rotated, and re-scaled under controlled conditions to assist with systematic validation of clinical systems.
More extensive deformations can be applied using the ImSimQAdform module.
Testing image registration algorithms without the scanner
ImSimQA is used to test rigid and deformable image registration algorithms found in today’s image fusion packages, IGRT treatment machines, auto-contouring and dose mapping in treatment planning applications.
For image registration testing, varying setups of an initial DICOM image series can be created, without having to use valuable scanner time to create multiple scans for testing. Initial high-resolution images e.g. 1mm slice spacing can be resampled to 2,3,5mm etc and exported to test the effect of slice resolution. RT Structure outlines can be edited, and structure densities can be allocated a new density prior to export – to test the effect of density differences on image registration accuracy.
Editing Real DICOM Images
Editing DICOM images imported into ImSimQA is a powerful way of creating an infinite range of new test scenarios, without needing to re-scan or source patient images, yet apply systematic changes in a scientific and methodical fashion.
Any DICOM-3 image modalities such as CT, MR, PET, and radiation therapy images such as MVCT and CBCT, can be imported and extensively edited.
DICOM parameter editing
DICOM header and image acquisition parameters such as name, UID, slice and FOV resolution can be edited and new parameters saved for export.
Density changes and RT Structures
An imported CT series with associated RT Structures can easily be edited to change the density of a contoured structure such as the bladder. A user-defined Hounsfield value can be assigned and the newly created images exported for testing. An example of this would be to apply a density for contrast media to the bladder in an IGRT-CBCT or planning CT image series, to test how image registration and fusion software performs with varying densities.
Virtual Phantom Library & Editing
ImSimQA provides a toolkit of 15 virtual phantoms that can be extensively edited and transformed, before being converted to DICOM CT, MR & PET simulated images. With the ability to add noise, change density, change slice spacing and re-orientate, the phantom DICOM images are then exported to the test application, minimising the use of the real scanner, and increasing the efficiency of testing. Real DICOM images can also be imported into ImSimQA for editing, without having to continually re-scan.